NIGERIAN JOURNAL OF SCIENCE AND ENVIRONMENT
Journal of the Faculties of Science and Agriculture, Delta State University, Abraka, Nigeria
ISSN: 1119-9008
DOI: 10.5987/UJ-NJSE
Email: njse@universityjournals.org
A COMPARATIVE STUDY ON THE ANTITODAL EFFECTS OF GARLIC (ALLIUM SATIVUM) AND GINGER (ZINGIBER OFFICINALE) ON BIRDS EXPOSED TO CYANIDE
DOI: 10.5987/UJ-NJSE.16.054.1 | Article Number: F82F7F5 | Vol.14 (1) - July 2016
Author: Kadiri H. E.
Keywords: Cyanide intoxication, garlic extract, ginger extract, antidotes
This study was based on the antitodal effect of aqueous garlic (Allium sativum) and ginger extract (Zingiber officinale) in broiler birds given different concentrations of cyanide by gavage for 6 weeks. A total of twenty four birds were used in the study. The birds were divided into 4 groups labeled Group A (normal control), Group B (cyanide control), Group C (cyanide and garlic) and Group D (cyanide and Ginger) respectively. Each group contains six birds each. Each bird was weighed and cyanide was administered according to their body weight every morning. The levels of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) was determined calorimetrically. The levels of lipid peroxidation, superoxide dismutase (SOD), catalase and glutathione peroxidase was also determined in the liver and organs of the birds by standard biochemical procedures. The results obtained showed a significant increase (P<0.05) in serum AST and ALT level in group C and D birds when compared with group A (normal control). However a significant decrease (P>0.05) in AST and ALT activity was recorded in Group C and D when compared with group B (cyanide control); similar result was recorded in alkaline phosphatase (ALP) activities. A significant decrease in lipid peroxidation level was also recorded in the liver and kidney of group C and D birds when compared with group B birds. Catalase and superoxide dismutase and glutathione peroxidase activity was also significantly higher in the liver and kidney of Group C birds when compared with group B birds. The results obtained from the study indicated that most of the investigated parameters were significantly remedied in the cyanide treated with garlic and ginger groups when compared with the untreated groups. It was also observed from the result of this research that garlic and gingers has promising roles and worthy to be considered as natural antidote for cyanide intoxication.
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