NIGERIAN JOURNAL OF SCIENCE AND ENVIRONMENT
Journal of the Faculties of Science and Agriculture, Delta State University, Abraka, Nigeria
ISSN: 1119-9008
DOI: 10.5987/UJ-NJSE
Email: njse@universityjournals.org
ACTIVITIES OF EXTRACTS OF NEGRO-PEPPER (XYLOPIA AETHOPICA) AND CASHEW (ANARCARDIUM OCCIDENTALE) ON SOME ANTIBIOTIC RESISI- TANT CLINICAL ISOLATES FROM BAPTIST MEDICAL CENTRE, EKU, DELTA STATE, NIGERIA
DOI: 10.5987/UJ-NJSE.17.078.3 | Article Number: D23B084 | Vol.10 (3) - December 2011
Authors: Akpomie O. O. and Ossai C. E.
Aqueous and ethanolic extracts of Xylopia aethiopica an Anacarduim occidentale obtained from Abraka main market, Delta State were analysed for their activities against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. The phytochemical analy- sis of the plants showed that they contain Alkaloids, Tannins, Saponins, flavonoids, Glycosides and chalcones. The antibiotics sensitivity pattern of S.aureus revealed resistance against Aug- mentin, Amoxycillin, Cloxacillin, Cotrimoxazole while E. coli, K. pneumoniae and P. aeruginosa were all resistant to Nalixidic and Ampicillin and had varying degrees of resistance to other antibiotics. S. aureus was sensitive to all the extracts at a minimum concentration of 12.5 % (v/v) of A. occidentale and at 50% (v/v) of x. aethiopica at minimum inhibitory concentration of 25% (v/v). E. coli was resistant to all the extracts but growth of all the organisms was inhibited when the extracts were applied in combination.
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