NIGERIAN JOURNAL OF SCIENCE AND ENVIRONMENT
Journal of the Faculties of Science and Agriculture, Delta State University, Abraka, Nigeria

ISSN: 1119-9008
DOI: 10.5987/UJ-NJSE
Email: njse@universityjournals.org

EFFECT OF MODERATE INTAKE OF A MIXTURE OF GARCINIA KOLA AND HONEY ON BLOOD CELLS

DOI: 10.5987/UJ-NJSE.16.066.1   |   Article Number: 5328E117   |   Vol.14 (1) - July 2016

Authors:  Popoola. A. O , Dare N. W , Avwioro O. G and

ABSTRACT

Full-Text PDF

A mixture of Garcinia kola and honey has been used for the treatment of certain conditions including dry coughs. The aim of this study was to study the effect of the mixture of G. kola and honey on blood cells. Twenty five rats were grouped into 5 of 5 rats each. A mixture of G. kola 0.16 g/kg and 0.5 ml honey was given orally to rats in Group 1 twice daily for 14 days. Each rat in Group 2 had a mixture of 0.20 g/kg G.a kola and 0.5 ml honey for a similar period as Group 1, while Groups 3 and 4 rats had 0.24g/kg G. kola and 0.5 ml honey, and 0.28 g/kg G. kola and 0.5 ml honey respectively. Group 5 served as the control, and was not administered with the mixture of G. kola and honey. The result did not reveal any significant difference in the packed cell volume (PCV), leucocyte differential count and the total leucocyte count in the control and test animals. Moderate intake of the mixture of G. kola and honey does not affect production of leucocytes and red bloodcells.

Akinnibosun, F. I.,  Itedjere, E. (2013). Evaluation of the antibacterial properties and synergistic effect of Garcinia kola Heckel (Family: Guttiferae) seed extract and honey on some bacteria. African Journal of Microbiology Research, 7(3): 174-180.

Avwioro, O. G., Demehin, A. O., Onyije, F. M., Bini, N., Oladele, A. A., Umukoro, S. (2014). The effect of oral administration of the mixture of Honey and Garcinia kola on the kidney of Wistar rats African Journal of Cellular Pathology, 3:35-38.

Chris, E. L. (2014). The impact and effect of bitter kola on honey. International Journal of Science and Technology, 5(10) 231-241.

Egunyomi, A., Moody, J. O., Eletu, O. M. (2009). Antisickling activities of two ethnomedicinal plant recipes used for the management of sickle cell anaemia in Ibadan, Nigerian (2009). African Journal of Biotechnology, 8:20-25.

Essien, D. E., Nwafor, P. E. (2014). Anticonseptive, estrogenic and antiestogenic potentials of methanol extract of Garcinia kola seed in rodents. Journal of Medicinal Plant Research, 8(42): 1237-1244.

Etkin, N. L. (1981). A hausa herbal pharmacopoeia: Biomedical evaluation of commonly used plant medicines. Journal of Ethnopharmacology, 4:75-98.

Farombi, E. O., Nwankwo, J. O., Emerole,  G. O. (2003). Evaluation of the antioxidant and partial characterization of extracts from browned yam flour. Food Research International, 6:33.

Fiorani, M., Accorsi, A., Blasa, M., Diamantini, G., Piatti, E. (2006). Flavonoids from Italian multifloral honey reduce the extracellular ferricyanide in human red blood cells. Journal of Agricultural and Food Chemistry, 54: 8328-8334.

Iwu, M. M., Igboko, O. (1982). Flavonoids of Garcinia kola seeds Journal of Natural Product, 45:650-651.

Kabangu, L., Galeffi, C., Aonzo, E., Nicoletti, M., Messana, I. (1987). New biflavone from the bark of G. Kola. Planta Medica, 11:275 – 277.

Kagbo, H., Ejebe, D. (2009). Phytochemistry and preliminary toxicity studies of the methanol extract of the stem bark of Garcinia kola (Heckel). The Internet Journal of Toxicology, 7: 2.

Keay, R.W.J., Onochie, C.F.A., Stanfield, D.P. (1964). Nigerian Trees. Vol. 1 Department of Forest Research, Ibadan, Nigeria, pp 51-54.

Martos, I., Ferreres, F., Tomás-Barberán, F. (2000). Identification of flavonoid markers for the botanical origin of Eucalyptus honey. Journal of Agricultural and Food Chemistry, 48:1498–1502.

Nanyak, Z. G., Ibraheem, M.G., Ali, A.H., Ali, I. S. (2013). The Effect of Aqueous Extract of Garcinia Kola Seed on the liver Histology. Journal of Natural Sciences Research, 3:81-87.

Ncube, N.S., Afolayan, A.J., Okoh, A.I. (2008). Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends. African Journal of Biotechnology, 7(12):1797-1806.

Ogunmoyole, T., Olalekan, O.O., Fatai, O., Makun, J. O., Kade, I. J. (2012). Antioxidant and phytochemical profile of aqueous and ethanolic extract of Garcinia kola. Journal of Pharmacognosy and Phytotherapy, 4:66-74.

Pand, K. N. (2014). Simple yoga for good health. India Star Publications, pp.100-104 .

Philip, J. L. (2014). A preliminary assessment of the glycemic index of honey.A report for the rural industries research and development corporation. pp.1-12.

Standifer, L. N., (2007). Honey Bee Nutrition and Supplemental Feeding. Excerpt from Beekeeping in United States.

Udenze, E.C.C., Braide, V. B., Okwesilieze, C.N., Akuodor, G. C, Odey, M. O. (2012). The effects of gavage treatment with Garcinia kola seeds on biochemical markers of liver functionality in diabetic rats. Annals of Biological Research, 3(9):4601-4608.

Vanghn, M., Bryant, J. R. (2001). Pollen contents of honey. AP Newspaper, (1) 10-24.